Sernivo bottle

A formulation
like no other topical
for mild-to-moderate plaque psoriasis

  • A Versatile Formulation for a Variety of Patients

  • 1. Elbows and Knees

    In Phase III clinical trials, over one-third of all target lesions were on elbows and knees.¹

  • 2. Hairy Areas

    Sernivo features a patented oil-in-water emulsion and may be easily sprayed on hairy areas.2

  • 3. Widespread Plaques

    Subjects in clinical studies had 10% to 20% of their body surface area affected.3

Sernivo is indicated for patients with mild-to-moderate plaque psoriasis, 18 years and older.
Enrolled patients had body surface area of involvement between 10% and 20%, and an Investigator Global Assessment (IGA) score of 3 (moderate).

Step 1: Shake the bottle
Remove the cap from the pump top.

Step 2: Push the pump
Hold the bottle upright. Point the opening of the pump top toward the affected area. To spray, push down on the pump top. NOTE: At first use, you may need to press the pump once or twice before Sernivo can be sprayed.

Step 3: Rub into skin
Spray only enough Sernivo to cover the affected area. Rub in gently. Replace the cap.

Download the complete instructions for use

Adverse reactions and efficacy were assessed at days 4, 8, 15, and 29. Sernivo has been shown to be well-tolerated for patients to use for up to 4 weeks, as treatment duration in clinical trials did not extend beyond that time.

Sernivo is the first oil-in-water emulsion (betamethasone dipropionate) delivered as a spray, making it a highly versatile topical. The patented Sernivo formulation has been proven to penetrate and permeate skin layers.2,4

The active ingredient is betamethasone dipropionate. Other ingredients include butylated hydroxytoluene, cetostearyl alcohol, hydroxyethyl cellulose, methylparaben, mineral oil, oleyl alcohol, polyoxyl 20 cetostearyl ether, propylparaben, purified water, and sorbitan monostearate.